Product Name:Humanin (human)
CAS No.:330936-69-1
Synonyms:Humanin (human) trifluoroacetate;抗凋亡肽;Humanin
Catalog No.:163P02
Brand:HongTide(上海鸿肽生物)
Description:Humanin 是一种24个氨基酸组成的抗凋亡肽,是Bax抑制剂。Humanin可以阻止Bax从细胞质向线粒体的转运,阻断Bax由活性构象向活性构象的转变。Humanin是一种线粒体相关肽,具有对抗 AD 相关神经毒性的神经保护作用,能够抑制由家族性阿尔茨海默病基因和淀粉样β蛋白(人)诱导的神经元细胞死亡。Humanin 还可以改善动物的整体胰岛素敏感性。Humanin还与衰老有关。
Humanin is an anti-apoptotic peptide composed of 24 amino acids and is a Bax inhibitor. Humanin can prevent the transport of Bax from cytoplasm to mitochondria, and block the transition of Bax from active conformation to active conformation. Humanin is a mitochondrial related peptide that has neuroprotective effects against AD related neurotoxicity and can inhibit amyloidosis caused by familial Alzheimer's disease genes β Protein (human) induced neuronal cell death. Humanin can also improve the overall insulin sensitivity of animals. Humanin is also related to aging.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | MAPRGFSCLLLLTSEIDLPVKRRA |
Sequence(3-letter code) | H-Met-Ala-Pro-Arg-Gly-Phe-Ser-Cys-Leu-Leu-Leu-Leu-Thr-Ser-Glu-Ile-Asp-Leu-Pro-Val-Lys-Arg-Arg-Ala-OH |
Peptide Structure |
|
Molecular Formula | C119H204N34O32S2 |
Molecular Weight | 2687.27 |
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上海鸿肽生物科技有限公司
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邮箱:sales1@hongtide.com
关键字: Humanin (human);330936-69-1;抗凋亡肽;Humanin;多肽;
上海鸿肽生物科技有限公司(简称:鸿肽生物)是一家以多肽以及多肽上下游产品研发、生产、销售以及技术转让为主要业 务科技公司。公司现有产品涵盖:定制多肽、目录多肽、氨基酸衍生物、小分子化合物;公司自成立以来,秉持“用质量作船, 以服务为帆,为科研服务”的企业理念,为国内外众多科研工作者提供了优质的服务及产品。