Host:Rabbit
Target Protein:Lamin B1
IR:Immunogen Range:
Clonality:Monoclonal
Isotype:IgG
Entrez Gene:4001
Swiss Prot:P20700
Source:KLH conjugated synthetic peptide derived from human Lamin B1:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
Background:The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD). [provided by RefSeq, Oct 2010].
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-1000)
IP(1:20-50)
IHC-P(1:100-500)
IHC-F(1:100-500)
ICC(1:50-200)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
本产品仅供科研使用。不能用于人和动物治疗等其它临床诊断使用！
关键字： LMB1;LMN2;LMN;MGC111419;Lamin B1;
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