Rabbit Anti-MICA Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:MICA
IR:Immunogen Range:101-200/383
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:100507436
Swiss Prot:Q29983
Source:KLH conjugated synthetic peptide derived from human MICA:101-200/383
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The MHC class I chain-related (MIC) proteins are related to the Major histocompatibility complex (MHC) class I proteins which are ubiquitously expressed and mediate the recognition of intracellular antigens by cytotoxic T cells. The MHC class I chain-related (MIC) proteins are recognized by NKG2D, a receptor on NK and T cells, and promote anti-tumor activity. MICA, a member of the MIC family, is widely expressed on many tumors, and it is the MICA/NKG2D interaction that is thought to stimulate the anti-tumor reactivity by T lymphocytes. MICA is present in virtually every tissue except the nervous system, suggesting that MIC protein expression may only be one component of the anti-tumor activity of the immune system.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： MICA;MHC I a;MIC A; PERB11.1;Stress inducible cla;MICA_HUMAN;MIC A;MIC-A;
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