Rabbit Anti-RAMP1 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:RAMP1
IR:Immunogen Range:118-148/148
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:10267
Swiss Prot:Q9WTJ5
Source:KLH conjugated synthetic peptide derived from human RAMP1:118-148/148
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the RAMP family of single transmembrane domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin receptor like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin gene related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： RAMP1;calcitonin receptor ;RAMP 1;CRLR activity modify;receptor (G protein ; receptor activity m;Receptor activity mo;RAMP1_HUMAN;
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