Rabbit Anti-5-HTR3 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:5-HTR3
IR:Immunogen Range:301-400/484
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:3359
Swiss Prot:P46098
Source:KLH conjugated synthetic peptide derived from human 5-HTR3:301-400/484
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. Expressed in cerebral cortex, amygdala, hippocampus, and testis. Detected in monocytes of the spleen and tonsil, in small and large intestine, uterus, prostate, ovary and placenta. Belongs to the ligand-gated ionic channel (TC 1.A.9) family.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-200)
IHC-F(1:100-200)
IF(1:50-100)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Cow
本品仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： 5-HTR3;5 HT3A;HTR-3A;5 HT3A receptor;5 HT3R;HTR3;Htr3a;5HT3A_HUMAN;
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