Rabbit Anti-CHRNA4 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CHRNA4
IR:Immunogen Range:151-250/627
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1137
Swiss Prot:P43681
Source:KLH conjugated synthetic peptide derived from human CHRNA4:151-250/627
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a nicotinic acetylcholine receptor, which belongs to a superfamily of ligand-gated ion channels that play a role in fast signal transmission at synapses. These pentameric receptors can bind acetylcholine, which causes an extensive change in conformation that leads to the opening of an ion-conducting channel across the plasma membrane. This protein is an integral membrane receptor subunit that can interact with either nAChR beta-2 or nAChR beta-4 to form a functional receptor. Mutations in this gene cause nocturnal frontal lobe epilepsy type1. Polymorphisms in this gene that provide protection against nicotine addiction have been described.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： CHRNA4;holinergic receptor ;holinergic receptor ;ACRA4;ALPHA-4NACHR;BFNC;CHRNA4;EBN;
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