Rabbit Anti-KLF6 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:KLF6
IR:Immunogen Range:185-283/283
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1316
Swiss Prot:Q99612
Source:KLH conjugated synthetic peptide derived from human KLF6:185-283/283
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:KLF6 is a nuclear protein that has three zinc fingers at the end of its C-terminal domain, a serine/threonine-rich central region, and an acidic domain lying within the N-terminal region. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. The DNA binding and transcriptional activity of this protein, in conjunction with its expression pattern, suggests that this protein may participate in the regulation and/or maintenance of the basal expression of pregnancy-specific glycoprotein genes and possibly other TATA box-less genes. Two transcript variants encoding the same protein have been found for this gene.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Pig
Cow
Horse
Rabbit
![image.png image.png](/SupplyImg/2023-07-27/6382605916384775956961282.jpg)
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: KLF6;Kruppel-like factor ;B cell derived prote;BCD1;COPEB;Core promoter elemen;CPBP;KLF6_HUMAN;
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