Rabbit Anti-CD177 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:CD177
IR:Immunogen Range:521-650/818
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:499099
Swiss Prot:D3ZCH9
Source:KLH conjugated synthetic peptide derived from rat CD177:521-650/818
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegener's granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified. [provided by RefSeq, Apr 2014]
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
IHC-P(1:100-500)
Cross Reactive Species:Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: CD177;NB1 GP;PRV-1;HNA-2a;NB1 glycoprotein;RGD1562941;CD177 antigen;CD177_MOUSE;
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