Rabbit Anti-Phospho-CDK2 (Thr14) Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:Phospho-CDK2 (Thr14)
IR:Immunogen Range:EG(p-T)YG
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1017
Swiss Prot:P24941
Source:KLH conjugated Synthesised phosphopeptide derived from human CDK2 around the phosphorylation site of Thr14:EG(p-T)YG
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein kinase is highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2. It is a catalytic subunit of the cyclin-dependent protein kinase complex, whose activity is restricted to the G1-S phase, and essential for cell cycle G1/S phase transition. This protein associates with and regulated by the regulatory subunits of the complex including cyclin A or E, CDK inhibitor p21Cip1 (CDKN1A) and p27Kip1 (CDKN1B). Its activity is also regulated by its protein phosphorylation. Two alternatively spliced variants and multiple transcription initiation sites of this gene have been reported. cdk2 is a cell cycle protein closely related to Cdc2 (cdk1) that has proved useful as a marker of proliferation. cdk2 binds cyclin type A and E proteins and controls progression into S-phase.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
IHC-P(1:100-500)
IHC-F(1:100-500)
Flow-Cyt(1μg/Test)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Dog
Cow
Horse
Rabbit
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: Phospho-CDK2 (Thr14);p-CDH2 (Thr14);CDH2 (phospho-Thr14);CDH2 (phospho-T14);Cdc2 related protein;CDK2;p33(CDK2).;CDK2_HUMAN;
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