Goat Anti-human Fibrinogen Polyclonal Antibody
DATASHEET
Host:Goat
Target Protein:human Fibrinogen
IR:Immunogen Range:
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:2243
Swiss Prot:P02671
Source:Fibrinogen from human plasma:
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Fibrinogen is the main protein of blood coagulation system. It is a large protein and it consists of two identical subunits that contain three polypeptide chains: alpha, beta and gamma. All chains are connected with each other by a number of disulfide bonds. Fibrinopeptides A (1 to 16 amino acids) and B (1 to 17 amino acids) are released by thrombin from the N terminal parts of alpha and beta chains, respectively. In this way fibrinogen is converted into fibrin, which by means of polymerization forms a fibrin clot. Fibrinogen clotting underlies pathogenesis of MI, thromboembolism and thromboses of arteries and veins, since fibrin is the main substrate for thrombus formation. Fibrinogen activation is also involved in pathogenesis of inflammation, tumor growth and many other diseases.
Size:50ul
Concentration:1mg/ml
Applications:WB(1:500-2000)
ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: human Fibrinogen;FGA;FGB;FGG;Fib2;Fibrin alpha chain;MGC119423;FIBA_HUMAN;
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