Rabbit Anti-GABA Transporter 2 Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:GABA Transporter 2
IR:Immunogen Range:131-230/602
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:6540
Swiss Prot:Q8TCC2
Source:KLH conjugated synthetic peptide derived from human GABA Transporter 2/GAT-2:131-230/602
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:GABA is a major inhibitory neurotransmitter and the GABAergic transmission is terminated by the rapid Na+/Cl-dependent uptake of through GABA transporters. There are multiple subtypes of GABA transporters (GAT1, GAT2, GAT3; and betaine GABA transporter (BGT-1). There is ~50% homology between each subtypes. GAT1 and GAT3 have been detected in various parts of the brain while GAT2 is found in many tissues. It appears that GAT1 and GAT3 are involved in distinct GABAergic transmission while GAT2 may be important in non-neural functions. GAT2 is a gamma-amino butyric acid (GABA) transporter. It is a 602 amino acid (85kDa) transmembrane protein.
Size:50ul
Concentration:1mg/ml
Applications:ELISA(1:5000-10000)
Cross Reactive Species:Human
Mouse
Rat
Chicken
Dog
Pig
Cow
Horse
Rabbit
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用!
关键字: GABA Transporter 2;GABA transport prote;GAT 2;GAT2;Solute carrier famil;GABA; member 13;S6A13_HUMAN;
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