Rabbit Anti-HBEGF Polyclonal Antibody
DATASHEET
Host:Rabbit
Target Protein:HBEGF
IR:Immunogen Range:20-62/208
Clonality:Polyclonal
Isotype:IgG
Entrez Gene:1839
Swiss Prot:Q99075
Source:KLH conjugated synthetic peptide derived from human DTSF/HB-EGF:20-62/208
Purification:affinity purified by Protein A
Storage:0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
Background:Heparin-binding epidermal growth factor-like growth factor (HB-EGF) is a 22kDa O-glycosylated protein that is a potent mitogen and chemoattractant for vascular smooth muscle cells, fibroblasts and epithelial cells but not endothelial cells. The natural protein has an apparent molecular mass of 19-23 kDa and exists in multiple forms as a result of heterogeneous O-glycosylation and/or Nterminal truncation. HB-EGF is synthesized as a membrane-anchored precursor(proHB-EGF) that is proteolytically cleaved to release the soluble mature growth factor. The two forms are active as juxtacrine and paracrine/autocrine growth factors respectively.HB-EGF activates two EGF receptor subtypes, HER1/ErbB1 and HER4 and binds to heparan sulfate proteoglycan.
Size:50ul
Concentration:1mg/ml
Applications:IHC-P(1:100-500)
IHC-F(1:100-500)
IF(1:100-500)
Cross Reactive Species:Human
Mouse
Rat
Pig
Cow
Sheep
仅供科研使用。不能用于人和动物治疗等其它临床诊断用！
关键字： HBEGF; DT R;Diphtheria toxin rec;DTR;DTS;DTSF;HEGFL;HBEGF_HUMAN;
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