佛手柑素,7380-40-7

一般描述

Bergamottin, a member of the furanocoumarin family, is primarily found in grapefruit juice. It is reported to be a novel signal transducer and activator of the transcription 3 (STAT3) inhibitor. It is a known drug inhibitor of cytochrome P450 34A and also exhibits diverse anti-tumor and anti-inflammatory activities.

应用

Bergamottin may be used as an analytical standard to test its efficacy in the following:
Blocker of STAT3 activation pathway in tumor cells; its potential in the therapy of multiple myeloma (MM) and other cancers is investigated.Prevention and the treatment of cancer via suppression of the NF-kB signaling pathway and its regulated gene products.