别名
N-(4-Aminobutyl)-5-chloro-2-naphthalenesulfonamide hydrochloride,W13
生化/生理作用
W-13 has also been shown to inhibit the transcytosis of IgA, recycling of transferrin and overall alter the endocytic pathway in Madin-Darby canine kidney cells. W-13 is a membrane-permeable calmodulin antagonist. W-13 inhibits Ca2+-calmodulin-dependent phosphodiesterase and has been shown to inhibit the EGF-dependent activation of EGFR in N7xHERc fibroblasts.
Sigma-Aldrich西格玛奥德里奇(上海)贸易有限公司
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