中文名:三乙烯硫代磷酰胺
英文名:Tri(1-aziridinyl)phosphine sulfide
纯度:Moligand™,≥98%
货号:T123963
Cas号:52-24-4
存储温度:2-8°C储存,充氩
运输条件:低温运输
产品介绍:
The unstable nitrogen-carbon groups alkylate with DNA which causes irreversible DNA damage. They stop tumor growth by crosslinking guanine nucleobases in DNA double-helix strands, directly attacking DNA. The DNA strands are unable to uncoil and separate which halts cell division.Thio-TEPA (N,N’N’-triethylenethiophosphoramide) is used as a cancer chemotherapeutic, alkylating agent. It is used to treat various kinds of cancer such as breast, ovarian and bladder cancer. It is also used as conditioning treatment prior to haematopoietic progenitor cell transplantation (HPCT).
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