中文名:2-溴-4′-甲氧基苯乙酮
英文名:2-Bromo-4′-methoxyacetophenone
中文别名:4-甲氧基苯甲酰基甲基溴|ω-溴-4-甲氧基苯乙酮|α-溴-4-甲氧基苯乙酮|4-(溴乙酰基)苯甲醚|2-溴-4'-甲氧基苯乙酮
英文别名:2632-13-5|2-Bromo-4'-methoxyacetophenone|2-Bromo-1-(4-methoxyphenyl)ethanone|Ethanone, 2-bromo-1-(4-methoxyphenyl)-|p-Methoxyphenacyl bromide|4-Methoxyphenacyl bromide|PTP Inhibitor II|PTP inhibitor 1|2-bromo-1-(4-methoxyphenyl)ethan-1-one|4'-Methoxyphena
纯度:98%
货号:B101897
包装:100g、25g、5g
Cas号:2632-13-5
存储温度:2-8°C储存
产品介绍:
PTP inhibitor II is a cell-permeable, covalent and potent PTP (protein tyrosine phosphatase) inhibitor. The compound acts by binding the catalytic domain of the SH2 domain-containing phosphatase SHP-1(DSH2). PTP inhibitor II binds with lower affinity than PTP Inhibitor I (Ki = 128 μM and Ki = 43 μM respectively). The inhibition can be reversed by irradiation of the inactivated PTP at 350 nm. PTP inhibitors have demonstrated enhanced clonogenic survival, mutagenesis and cell growth. PTP inhibitors can also be useful for probing signal transduction pathways as well as drμgs for treatment of PTP-related diseases. PTP Inhibitor II is an inhibitor of PTP1B and SH-PTP1.A cell-permeable, covalent and potent protein tyrosine phosphatase inhibitor.
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