中文名:二苯基硼酸-2-氨基乙酯
英文名:2-Aminoethyl diphenylborinate
应用:用于黄酮类化合物的密度测定。膜渗透调控因子,调控细胞间IP3诱导的钙离子释放。
纯度:Moligand™,≥98%
货号:A106408
Cas号:524-95-8
存储温度:-20°C储存,充氩
运输条件:超低温运输
产品介绍:
2-APB is a transient receptor potential (TRP) activator. The compound also directly blocks the mitochondrial permeability transition pore, sarco/endoplasmic reticulum Ca2+-ATPase pumps, and native store operated channels, as well as other ion channels. 2-APB does not activate the subfamily transient receptor potential vanilloids (TRPVs) TRPV4, TRPV5, and TRPV6, but can activate VR1 (TRPV1), VRL-1 (TRPV2), and TRPV3. 2-ABP was first used as an inhibitor of IP3R (inositol 1,4,5-triphosphate receptor) with the ability to permeate the membrane. 2-ABP can induce Ca2+entry without activating exocytosis. In pancreatic acinar cells 2-ABP can inhibit calcium mobilization. 2-APB is an activator of Orai3.用于黄酮类化合物的密度测定。膜渗透调控因子,调控细胞间IP3诱导的钙离子释放。
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