中文名:依利罗地
英文名:Eliprodil
英文别名:Eliprodil|119431-25-3|Eliprodil [INN]|C20H23ClFNO|SL-820715|alpha-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol|1-(4-chlorophenyl)-2-[4-[(4-fluorophenyl)methyl]piperidin-1-yl]ethanol|CHEMBL28564|YW62A6TW29|DTXSID1045744|1-Piperidineethan
纯度:≥98% (HPLC)
货号:E137445
包装:10mg、50mg
Cas号:119431-25-3
存储温度:2-8°C储存
产品介绍:
Eliprodil is a non-competitive NMDA receptor antagonist which acts at the polyamine modulatory site. Eliprodil is selective for NMDA epsilon 2 (NR2B-containing receptors) over NR2A- and NR2C-containing receptors (IC50 values are 1, > 100 and > 100 μM respectively) in addition to acting as a Sigma Receptor (σ1 ligand) (Ki = 0.013 μM). Eliprodil antagonizes neuronal voltage-gated Ca2+ channels and selectively inhibits the rapid component of the delayed rectifier K+ current (IKr). Furthermore, Eliprodil is reported to act as a neuroprotective.
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