中文名:醋酸钯
英文名:Palladium acetate
纯度:≥99.98% metals basis
货号:P111486
Cas号:3375-31-3
存储温度:室温,干燥,阴凉
运输条件:常规运输
产品介绍:
Product class
M-O, Homogeneous Catalysts, Acetate Ligands
Reaction type
Cross Coupling Reactions with Arenes, CH-Activation, Carbonylation, Mizoroki Heck Coupling Reaction, Sonogashira-Hagihara Coupling Reaction, Suzuki-Miyaura Coupling Reaction, Oxidation
Chemical properties
Theoretical metal content
Applications & references
Synthesis of 2-(4-{2-[(2R)-2-Cyclopentyl-5-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylmethyl)-4-hydroxy-6-oxo-3,6-dihydro-2H-pyran-2-yl]-ethyl}-2-fluoro-phenyl)-2-methyl-propionitrile on multikilogram scale using a merging Heck coupling reaction. Compound is an inhibitor of the hepatitis C viral polymerase (HCVP) enzyme.

Reference: Org. Proc. Res. Dev. 2006, 10, 814. (DOI: 10.1021/op0600761)
Reductive carbonylation of aryl halides as an alternative and mild route for the introduction of aldehyde functionality, which is mostly desired for fine chemical and pharmaceutical intermediates to open up the wide range of further possible transformations.

Reference: Org. Proc. Res. Dev. 2007, 11, 39. (DOI: 10.1021/op060193w)
Synthesis of the pyrazolopyridinone-based p38 mitogen-activated protein kinase inhibitor including a Suzuki coupling reaction. p38 MAP kinases are intercellular serine/threonine kinases which certainly regulate the production and action of several pro-inflammatory mediators. They are also involved in disease states such as rheumatoid arthritis, Crohn’s diseases and psoriasis.

Reference: Org. Proc. Res. Dev. 2011, 15, 31. (DOI: 10.1021/op100205s)
Efficient hydroformylation of aryl triflates.

Reference: Synthesis 1996, 470 (DOI: 10.1055/s-1996-4246)
Deacetylation-Diazotation-Heck-Sequence: Carbon-Carbon bond formation with acetanilides as formal leaving groups

Reference: Adv. Synth. Catal. 2013, 355, 463 (DOI: 10.1002/adsc.201200929)
Deacetylation-Diazotation-Suzuki-Sequence: Carbon-Carbon bond formation with acetanilides as formal leaving groups.

Reference: Adv. Synth. Catal. 2013, 355, 463 (DOI: 10.1002/adsc.201200929)
Deacetylation-Diazotation-[2+2+1]-Cycloaddition:

Reference: Adv. Synth. Catal. 2013, 355, 463 (DOI: 10.1002/adsc.201200929)
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关键字: 乙酸钯;Palladium (II) acetate ; SR-01000389719 ; EU-0040175
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