中文名:1,2-二溴乙烷-1-磺酰氟
英文名:1,2-Dibromoethane-1-sulfonyl fluoride
纯度:≥90%
货号:D486510
Cas号:103020-97-9
存储温度:室温
产品介绍:
1,2-Dibromoethane-1-sulfonyl fluoride (DESF) is a bench-stable precursor to 1-bromoethene-1-sulfonyl fluoride (BESF), a new and robust connective hub for the Sulfur (VI) fluoride exchange (SuFEx) click reaction. BESF offers similar routes as ethenesulfonyl fluoride (ESF, cat#746959) but with additional reactivity due to the embedded bromo group.Treatment of DESF with triethylamine generates BESF in situ, which has been used to synthesize diverse and unprecented sulfonyl fluorides in good-to-excellent yields. As the resulting molecules possess sulfonyl fluoride handles, further SuFEx reactions are also possible. DESF adds another useful tool for conjugation strategies in chemical biology and organic and polymer synthesis.
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