Mouse IL-2 R beta Protein, His Tag
分子别名(Synonym)
IL2RB,RP5-1170K4.6,CD122,P70-75
表达区间及表达系统(Source)
Mouse IL-2 R beta, His Tag (ILA-M52H5) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Glu 240 (Accession # P16297-1).
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the C-terminus.
The protein has a calculated MW of 27.1 kDa. The protein migrates as 42-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
白细胞介素-2受体(IL-2R)是一种异三聚体蛋白,在某些免疫细胞(如淋巴细胞)的表面表达,结合并响应称为IL-2的细胞因子。IL-2R由3个亚基-α(CD25)、β(CD122)和γ(CD132)-非共价结合组成。α链和β链参与结合IL-2,而细胞因子相互作用后的信号转导由γ链和β亚基进行。
CD122也被称为IL2Rβ,是I型细胞因子受体家族的成员。CD122是白细胞介素-2的受体,参与受体介导的内吞作用,并转导IL2的促有丝分裂信号。
关键字: IL-2 R beta;IL-2 R beta蛋白;IL2RB重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。