ENPP-2产品信息
英文名称:Ectonucleotide pyrophosphatase/phosphodiesterase 2
中文名称:核苷酸内焦磷酸酶/磷酸二酯酶2
靶点别称:ENPP-2
物种:Human
标签:His Tag
属性:Protein
标记:Unconjugated
表达区间及表达系统(Source)
Human ENPP-2, His Tag (EN2-H5241) is expressed from human 293 cells (HEK293). It contains AA Asp 49 - Ile 863 (Accession # NP_001035181).
Predicted N-terminus: His
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 94.5 kDa. The protein migrates as 90-100 kDa under reducing (R) condition (SDS-PAGE).
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 150 mM NaCl, pH7.5 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.


背景(Background)
Autotaxin也称为外核苷酸焦磷酸酶/磷酸二酯酶家族成员2(E-NPP 2或ENPP2)、细胞外溶血磷脂D(LysoPLD)、自身滑行素(ATX或ATX-X),属于核苷酸焦磷酸酶或磷酸二酯酶家庭。ENPP2包含两个SMB(somatomedin-B)域。ENPP2水解溶血磷脂,在细胞外液中产生溶血磷脂酸(LPA)。ENPP2可以作用于产生鞘氨醇-1-磷酸的鞘氨醇磷脂酰胆碱,这是一种细胞运动的调节剂。ENPP2可能通过百日咳毒素敏感的G蛋白刺激黑色素瘤细胞的迁移。
关键字: ENPP2;ENPP2蛋白;ENPP2重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。