Stathmin 1产品信息
英文名称:Stathmin
中文名称:Stathmin蛋白
靶点别称:STMN1,Stathmin 1,C1orf215,LAP18,OP18
物种:Human
标签:His Tag
属性:Protein
标记:Unconjugated
表达区间及表达系统(Source)
Human Stathmin 1, His Tag (ST1-H5149) is expressed from E. coli cells. It contains AA Ala 2 - Asp 149 (Accession # NP_981946).
Predicted N-terminus: Met
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 18.1 kDa. The protein migrates as 18 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method.
纯度(Purity)
>95% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景(Background)
Stathmin(STMN1)是Stathmin家族的成员,也被称为白血病相关磷蛋白p18、癌蛋白18(Op18)、磷蛋白p19(pp19)、蛋白Pr22和pp17,其中含有一个SLD(Stathmin样)结构域。STMN1作为微管动力学的重要调节蛋白的功能已得到很好的表征。Stathmin(STMN1)与两个二聚体α,β-微管蛋白分子相互作用,形成一个紧密的三元复合物,称为T2S复合物。一摩尔STMN1通过stathmin样结构域(SLD)与两摩尔微管蛋白二聚体结合。当STMN1将微管蛋白螯合到T2S复合物中时,微管蛋白变得不可聚合。没有微管蛋白聚合,就没有微管组装。STMN1还通过直接作用于微管末端来促进微管解体。
关键字: Stathmin;Stathmin蛋白;STMN1重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。