ACAD10抗体,Rabbit Polyclonal ACAD10 Antibody
  • ACAD10抗体,Rabbit Polyclonal ACAD10 Antibody
  • ACAD10抗体,Rabbit Polyclonal ACAD10 Antibody
  • ACAD10抗体,Rabbit Polyclonal ACAD10 Antibody

ACAD10抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-13
QQ交谈 微信洽谈

产品详情

中文名称:ACAD10抗体英文名称:Rabbit Polyclonal ACAD10 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 3716 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ACAD10
2025-05-13 ACAD10抗体 Rabbit Polyclonal ACAD10 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 3716 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/15-1/50 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human ACAD10
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P07741(ACAD10 Antibody) at dilution 1/10. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P07741(ACAD10 Antibody) at dilution 1/10. (Original magnification: ×200)    


           

参考文献

以下是关于ACAD10抗体的3篇参考文献及其摘要概括:

1. **文献名称**:*ACAD10 Expression in Non-Small Cell Lung Cancer: A Novel Prognostic Marker*

**作者**:Smith J, et al. (2020)

**摘要**:本研究利用自主研发的小鼠单克隆ACAD10抗体,通过免疫组化技术分析非小细胞肺癌组织样本,发现ACAD10高表达与患者生存期延长显著相关,提示其作为预后标志物的潜力。

2. **文献名称**:*Development and Validation of a Polyclonal Antibody for Detection of ACAD10 in Metabolic Disorders*

**作者**:Zhang L, et al. (2018)

**摘要**:作者报道了一种兔源多克隆ACAD10抗体的制备,并通过Western blot和免疫荧光验证其特异性。该抗体成功应用于肥胖模型中ACAD10蛋白水平变化的检测,揭示其与脂质代谢异常的相关性。

3. **文献名称**:*ACAD10 Localization and Function in Mitochondrial Fatty Acid Oxidation*

**作者**:Johnson R, et al. (2019)

**摘要**:研究使用商业ACAD10抗体(货号AB123.Sigma)进行亚细胞定位分析,确认ACAD10定位于线粒体,并通过敲低实验证明其在脂肪酸β氧化中的关键作用。

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**备注**:上述文献信息为示例,实际引用需根据真实发表的论文调整。建议通过PubMed或Web of Science以“ACAD10 antibody”为关键词检索最新文献。

       

背景信息

The ACAD10 antibody targets acyl-CoA dehydrogenase family member 10 (ACAD10), a mitochondrial enzyme belonging to the acyl-CoA dehydrogenase family, which plays a role in fatty acid β-oxidation. ACAD10 is implicated in cellular energy metabolism, though its precise substrate specificity and biological functions remain less characterized compared to other ACAD family members (e.g., ACADM or ACADVL). Recent studies suggest ACAD10 may regulate metabolic pathways beyond fatty acid oxidation, including interactions with mTOR signaling. For instance, ACAD10 upregulation has been linked to mTOR inhibition, influencing cell growth, autophagy, and stress responses.

Research highlights ACAD10's potential involvement in metabolic disorders, cancer, and longevity. In humans, ACAD10 variants are associated with type 2 diabetes and obesity, while its overexpression in certain cancers (e.g., lung adenocarcinoma) correlates with poor prognosis. ACAD10 antibodies are essential tools for detecting protein expression, localization, and quantification in tissues or cell lines, aiding investigations into its metabolic and disease-related roles. Commercial ACAD10 antibodies are typically validated for applications like Western blotting, immunohistochemistry, or immunofluorescence. However, specificity challenges may arise due to structural similarities within the ACAD family, necessitating careful validation. Ongoing research aims to clarify ACAD10's molecular mechanisms and therapeutic potential in metabolic and neoplastic diseases.

       
关键字: ACAD10抗体;ACAD10;ACAD10 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
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