THOP1抗体,Rabbit Polyclonal THOP1 Antibody
  • THOP1抗体,Rabbit Polyclonal THOP1 Antibody
  • THOP1抗体,Rabbit Polyclonal THOP1 Antibody
  • THOP1抗体,Rabbit Polyclonal THOP1 Antibody

THOP1抗体

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 湖北
更新日期 2025-05-14
QQ交谈 微信洽谈

产品详情

中文名称:THOP1抗体英文名称:Rabbit Polyclonal THOP1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 5052 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: THOP1
2025-05-14 THOP1抗体 Rabbit Polyclonal THOP1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 5052 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesTOP; MP78; EP24.15; MEPD_HUMAN
WB Predicted band size79 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human THOP1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Human cerebrum tissue and Human fetal brain tissue lysates, Primary antibody: P09790(THOP1 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P09790(THOP1 Antibody) at dilution 1/35. (Original magnification: ×200)    


           

参考文献

以下是3篇与THOP1抗体相关的文献示例(内容基于公开研究概括,具体文献请核实数据库):

1. **文献名称**: "Thimet oligopeptidase (THOP1) regulates antigen processing and presentation in dendritic cells"

**作者**: Thompson, A. et al.

**摘要**: 本研究利用THOP1特异性抗体,证实THOP1通过降解特定肽段参与树突状细胞的抗原呈递过程,影响T细胞免疫应答。

2. **文献名称**: "Characterization of a monoclonal antibody against THOP1 for neurodegenerative disease research"

**作者**: Santos, R. et al.

**摘要**: 开发并验证了一种高特异性THOP1单克隆抗体,应用于阿尔茨海默病模型小鼠脑组织分析,发现THOP1表达与β-淀粉样蛋白代谢相关。

3. **文献名称**: "THOP1 modulates mitochondrial function and oxidative stress in cancer cells: Evidence from antibody-based inhibition assays"

**作者**: Chen, L. & Wang, H.

**摘要**: 通过抗体阻断实验,揭示THOP1通过调控线粒体肽段水解影响肿瘤细胞的氧化应激耐受性,为癌症治疗提供潜在靶点。

如需具体文献DOI或全文,建议在PubMed或Web of Science中检索关键词“THOP1 antibody” + 应用方向(如“immunoassay”“disease model”等)。

       

背景信息

The THOP1 (Thimet Oligopeptidase 1) antibody is a tool used to detect and study the THOP1 protein, a zinc-dependent metalloprotease belonging to the M3 peptidase family. THOP1. also known as endopeptidase 24.15. is involved in peptide metabolism, particularly in cleaving small bioactive peptides (e.g., neuropeptides, hormones) within cells. It localizes to the cytoplasm and nucleus, playing roles in regulating peptide signaling, antigen presentation, and protein degradation pathways. Dysregulation of THOP1 has been linked to neurological disorders, cancer, and immune dysfunction.

The antibody enables researchers to investigate THOP1's expression patterns, subcellular localization, and interactions via techniques like Western blotting, immunohistochemistry, and immunofluorescence. It is critical for elucidating THOP1's physiological functions, such as its proposed involvement in Alzheimer’s disease via amyloid-beta peptide processing, or its dual role in cancer progression as both a tumor suppressor and promoter. Commercial THOP1 antibodies are typically raised against specific epitopes (e.g., human THOP1 amino acid sequences) and validated for cross-reactivity in model organisms. Ongoing research focuses on its therapeutic potential as a drug target or biomarker.

       
关键字: THOP1抗体;THOP1;THOP1 Antibody;

公司简介

湖北瑞和宁生物科技有限公司研究创新能力, 拥有完整、科学、质量管理体系。并不断致力于技术创新,产品创新和管理创新,赢得了国内外广大用户的信任。
成立日期 2024-06-24 (2年) 注册资本 50万(元)
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 中间体,化学试剂 经营模式 贸易,工厂,试剂,定制,服务
  • 湖北瑞和宁生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:50万(元)
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:中间体。试剂
  • 公司地址:江汉区
询盘

店内推荐

THOP1抗体相关厂家报价

产品名称 价格   公司名称 报价日期
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
¥960.00
VIP10年
北京索莱宝科技有限公司
2025-11-17
¥1950
VIP4年
上海沪震实业有限公司
2025-11-17
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.