PDLIM1抗体,Rabbit Polyclonal PDLIM1 Antibody
  • PDLIM1抗体,Rabbit Polyclonal PDLIM1 Antibody
  • PDLIM1抗体,Rabbit Polyclonal PDLIM1 Antibody
  • PDLIM1抗体,Rabbit Polyclonal PDLIM1 Antibody

PDLIM1抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-16
QQ交谈 微信洽谈

产品详情

中文名称:PDLIM1抗体英文名称:Rabbit Polyclonal PDLIM1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 2010 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: PDLIM1
2025-05-16 PDLIM1抗体 Rabbit Polyclonal PDLIM1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 2010 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/2000-1/5000 Human,Mouse,Rat
   

产品详情

AliasesCLIM1; CLP36; CLP-36; hCLIM1; HEL-S-112
WB Predicted band size36 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse, Rat
ImmunogenFusion protein of human PDLIM1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: A172 cells, Primary antibody: P01632(PDLIM1 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human colon cancer tissue using P01632(PDLIM1 Antibody) at dilution 1/30. (Original magnification: ×200)    


           

参考文献

以下是3篇关于PDLIM1抗体的参考文献示例(文献信息为虚构,仅供参考格式):

---

1. **文献名称**:PDLIM1 suppresses epithelial-mesenchymal transition in breast cancer through TGF-β/Smad signaling regulation

**作者**:Chen L, Wang Y, et al.

**摘要**:本研究利用PDLIM1特异性抗体进行Western blot和免疫组化分析,发现PDLIM1通过抑制TGF-β/Smad信号通路阻止乳腺癌细胞的EMT进程,提示其作为肿瘤转移抑制因子的潜在作用。

---

2. **文献名称**:PDLIM1 modulates nuclear factor-κB activity in inflammatory responses

**作者**:Kim S, Tanaka H, et al.

**摘要**:通过免疫共沉淀和免疫荧光技术(使用PDLIM1抗体),研究发现PDLIM1通过与NF-κB p65亚基相互作用,负调控炎症反应中NF-κB的活化,为炎症性疾病治疗提供新靶点。

---

3. **文献名称**:Aberrant PDLIM1 expression correlates with colorectal cancer progression

**作者**:Gupta R, et al.

**摘要**:采用PDLIM1抗体对结直肠癌组织进行免疫组化染色,发现PDLIM1低表达与肿瘤分期、转移及患者生存率显著相关,表明其可作为预后生物标志物。

---

**备注**:以上文献为示例,实际研究中建议通过PubMed、Web of Science等数据库检索真实文献(关键词:PDLIM1 antibody, PDLIM1 function)。

       

背景信息

**Background of PDLIM1 Antibody**

PDLIM1 (PDZ and LIM domain protein 1), also known as CLP-36 or CLIM1. is a cytoskeletal protein belonging to the PDZ-LIM family, characterized by its N-terminal PDZ domain and C-terminal LIM domain. It plays critical roles in cell adhesion, cytoskeletal organization, and signal transduction by interacting with actin-associated proteins, transcription factors, and signaling molecules. PDLIM1 is involved in regulating nuclear translocation of transcription factors like NF-κB and STAT, linking cytoskeletal dynamics to gene expression. Dysregulation of PDLIM1 has been implicated in cancer, inflammation, and cardiovascular diseases, with studies highlighting its dual roles as a tumor suppressor or promoter depending on context.

The PDLIM1 antibody is a vital tool for detecting and quantifying PDLIM1 expression in cells and tissues. It is widely used in techniques such as Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and flow cytometry to study its localization, protein-protein interactions, and functional mechanisms. Researchers employ this antibody to explore PDLIM1’s involvement in cellular processes, disease pathways, and therapeutic targeting. Validated for specificity and sensitivity, it aids in distinguishing PDLIM1 isoforms and post-translational modifications, providing insights into its context-dependent roles in health and disease. Commercial antibodies are typically raised in hosts like rabbits or mice, with clonal variants (monoclonal/polyoclonal) optimized for diverse experimental needs.

       
关键字: PDLIM1抗体;PDLIM1;PDLIM1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

PDLIM1抗体—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1950
VIP4年
上海沪震实业有限公司
2025-11-13
¥1600.00
VIP10年
北京索莱宝科技有限公司
2025-11-14
¥2700
VIP6年
上海泽叶生物科技有限公司
2025-11-13
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.