PTGES3L-AARSD1抗体—艾普蒂

+ +

•  

   

     The image is immunohistochemistry of paraffin-embedded Human tonsil tissue using P02919(PTGES3L-AARSD1 Antibody) at dilution 1/35. (Original magnification: ×200)    

  
  

The PTGES3L-AARSD1 antibody is designed to detect a protein complex or interaction involving prostaglandin E synthase 3-like (PTGES3L) and alanyl-tRNA synthetase domain-containing 1 (AARSD1). PTGES3L, a homolog of PTGES3. is implicated in cellular stress responses, though its enzymatic role in prostaglandin synthesis remains unclear. AARSD1. a member of the aminoacyl-tRNA synthetase family, is linked to mitochondrial translation and ribosome biogenesis. Their interaction may reflect a regulatory mechanism bridging metabolic pathways and translational control, potentially influencing cell survival or disease processes.

This antibody is commonly used in techniques like Western blotting, immunoprecipitation, or immunofluorescence to study the expression, localization, and functional interplay of these proteins. Research applications include investigating their roles in cancer progression, neurodegenerative disorders, or oxidative stress responses, as both proteins have been associated with pathways involving protein synthesis fidelity and stress adaptation. Specificity validation is critical, as cross-reactivity with individual proteins (PTGES3L or AARSD1) or unrelated isoforms could occur. Recent studies suggest the PTGES3L-AARSD1 axis may modulate mRNA stability or translation in stress granules, highlighting its emerging relevance in post-transcriptional gene regulation.