STX19抗体—艾普蒂

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     Gel: 10%SDS-PAGE, Lysate: 80 μg, Lane: 231 cell, Primary antibody: P08834(STX19 Antibody) at dilution 1/800, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds    

  
  

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     The image is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using P08834(STX19 Antibody) at dilution 1/35. (Original magnification: ×200)    

  
  

The STX19 antibody is a tool used to detect and study Syntaxin-19 (STX19), a member of the syntaxin family of proteins involved in intracellular membrane trafficking and vesicle fusion. Syntaxins are key components of the SNARE (Soluble NSF Attachment Protein Receptor) complex, which mediates membrane fusion events essential for cargo transport between organelles. While many syntaxins, such as STX1 and STX4. are well-characterized in processes like neurotransmitter release and glucose transporter trafficking, STX19 remains less studied. It is thought to localize to the Golgi apparatus or endosomal compartments, potentially regulating retrograde transport or organelle dynamics.

STX19 antibodies are typically developed as polyclonal or monoclonal reagents for applications like Western blotting, immunofluorescence, and immunoprecipitation. These antibodies help researchers investigate STX19’s expression patterns, subcellular localization, and interactions with other SNARE proteins or regulatory factors. Studies using STX19 antibodies may shed light on its role in cellular processes such as protein secretion, organelle biogenesis, or disease contexts like cancer or neurodegenerative disorders where membrane trafficking is disrupted. However, limited literature on STX19 highlights the need for further validation of antibody specificity and functional exploration. Commercial STX19 antibodies often include validation data in common cell lines or tissues, but researchers are advised to confirm target specificity through knockdown/knockout controls.