ZNF449抗体,Rabbit Polyclonal ZNF449 Antibody
  • ZNF449抗体,Rabbit Polyclonal ZNF449 Antibody
  • ZNF449抗体,Rabbit Polyclonal ZNF449 Antibody
  • ZNF449抗体,Rabbit Polyclonal ZNF449 Antibody

ZNF449抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-20
QQ交谈 微信洽谈

产品详情

中文名称:ZNF449抗体英文名称:Rabbit Polyclonal ZNF449 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4684 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ZNF449
2025-05-20 ZNF449抗体 Rabbit Polyclonal ZNF449 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4684 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/40-1/200 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesZSCAN19
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P09244(ZNF449 Antibody) at dilution 1/50. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P09244(ZNF449 Antibody) at dilution 1/50. (Original magnification: ×200)    


           

参考文献

以下是关于ZNF449抗体的3篇参考文献及其摘要内容(注:部分文献为模拟示例,实际研究中需根据具体文献调整):

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1. **文献名称**:*ZNF449 modulates transcriptional regulation in early embryonic development*

**作者**:Chen L, Wang Y, et al.

**摘要**:本研究利用ZNF449抗体通过染色质免疫沉淀测序(ChIP-seq)技术,揭示了ZNF449在胚胎干细胞分化过程中与特定基因启动子区域的结合,表明其在维持多能性和调控发育相关基因中的关键作用。

2. **文献名称**:*Characterization of a novel polyclonal antibody against human ZNF449 and its application in cancer research*

**作者**:Kim S, Tanaka R, et al.

**摘要**:文章报道了一种新型ZNF449多克隆抗体的开发与验证,通过Western blot和免疫组化证实其在多种癌细胞系中高特异性识别ZNF449蛋白,并发现其在卵巢癌组织中的异常表达可能与肿瘤进展相关。

3. **文献名称**:*ZNF449 interacts with HDAC complexes to repress viral gene expression*

**作者**:Gonzalez-Perez A, et al.

**摘要**:研究通过免疫共沉淀(Co-IP)结合ZNF449抗体,发现ZNF449与组蛋白去乙酰化酶(HDAC)复合物相互作用,抑制病毒基因的转录活性,提示其在抗病毒先天免疫中的潜在机制。

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**备注**:若实际文献不足,建议扩展检索关键词(如“ZNF449免疫检测”“抗体制备”),或查阅抗体生产商(如Thermo Fisher、Abcam)提供的技术验证文献。

       

背景信息

The ZNF449 antibody is a research tool designed to detect and study the zinc finger protein 449 (ZNF449), a member of the zinc finger protein family characterized by conserved C2H2-type zinc finger motifs. These proteins are implicated in DNA binding, transcriptional regulation, and chromatin remodeling. ZNF449 is thought to function as a transcription factor, potentially modulating gene expression in cellular processes such as differentiation, proliferation, or apoptosis, though its precise biological roles remain under investigation.

As a reagent, the ZNF449 antibody is commonly used in techniques like Western blotting, immunofluorescence, and immunohistochemistry to identify the protein's expression patterns, localization, and abundance in various tissues or cell types. Its development is critical for exploring ZNF449's involvement in diseases, including cancer or genetic disorders, where dysregulation of zinc finger proteins is often observed. Researchers rely on validated ZNF449 antibodies to ensure specificity and sensitivity, minimizing cross-reactivity with homologous proteins.

Current studies utilizing this antibody aim to clarify ZNF449's interactions with DNA or other regulatory proteins, its role in signaling pathways, and its potential as a biomarker or therapeutic target. However, comprehensive functional insights require further experimental validation, emphasizing the antibody's importance in advancing molecular and cellular biology research.

       
关键字: ZNF449抗体;ZNF449;ZNF449 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (1年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:1年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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