TEDC1抗体,Rabbit Polyclonal TEDC1 Antibody
  • TEDC1抗体,Rabbit Polyclonal TEDC1 Antibody
  • TEDC1抗体,Rabbit Polyclonal TEDC1 Antibody
  • TEDC1抗体,Rabbit Polyclonal TEDC1 Antibody

TEDC1抗体—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-20
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产品详情

中文名称:TEDC1抗体英文名称:Rabbit Polyclonal TEDC1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 4795 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: TEDC1
2025-05-20 TEDC1抗体 Rabbit Polyclonal TEDC1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 4795 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesC14orf80
WB Predicted band size54 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFusion protein of human TEDC1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-2:K562 cell and Human testis tissue lysates, Primary antibody: P09387(TEDC1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P09387(TEDC1 Antibody) at dilution 1/35. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P09387(TEDC1 Antibody) at dilution 1/35. (Original magnification: ×200)    


           

参考文献

以下是3篇假设的关于TEDC1抗体的参考文献(注:经核实,目前公开数据库中暂未收录真实相关文献,以下为模拟学术论文结构):

1. **文献名称**: "TEDC1 Antibody Development for Detecting Cell Cycle-Dependent Expression Patterns"

**作者**: Zhang L, et al.

**摘要**: 本研究开发了针对人类TEDC1蛋白的特异性多克隆抗体,验证了其在HeLa细胞中的Western blot和免疫荧光检测效果,发现TEDC1在G2/M期表达显著上调,提示其在细胞周期调控中的潜在作用。

2. **文献名称**: "TEDC1 as a Novel Biomarker in Glioblastoma: Validation by Immunohistochemistry"

**作者**: Watanabe K, et al.

**摘要**: 通过TEDC1抗体进行的免疫组化分析显示,TEDC1在胶质母细胞瘤组织中的表达水平与患者生存率呈负相关,表明其可能作为神经胶质瘤预后的生物标志物。

3. **文献名称**: "Functional Characterization of TEDC1 in DNA Repair Using CRISPR/Cas9 and Antibody-Based Assays"

**作者**: Müller S, et al.

**摘要**: 利用TEDC1特异性抗体结合基因编辑技术,证实TEDC1通过与BRCA1蛋白相互作用参与DNA双链断裂修复,抗体在染色质免疫沉淀(ChIP)实验中成功捕获TEDC1-DNA复合物。

(提示:若需真实文献,建议通过PubMed或Google Scholar以“TEDC1 antibody”或“TEDC1 function”为关键词检索最新研究。)

       

背景信息

The TEDC1 (Telomere-associated DN2-binding protein C1) antibody is a tool used to study the TEDC1 protein, which plays a role in telomere maintenance and genomic stability. TEDC1. also known as C16orf74. is involved in the telomere-length regulation complex and interacts with shelterin components, such as TERF1 and POT1. to modulate telomeric DNA replication and protection. Its function is critical in preventing telomere dysfunction, which can lead to chromosomal abnormalities, cellular senescence, or cancer progression. Research suggests TEDC1 may act as a tumor suppressor, with downregulation observed in certain cancers, including hepatocellular carcinoma and glioblastoma.

The TEDC1 antibody is widely utilized in molecular biology and cancer research to detect TEDC1 expression via techniques like Western blotting, immunofluorescence, and immunohistochemistry. It helps investigate TEDC1's involvement in cell cycle regulation, DNA damage response, and its potential crosstalk with pathways like p53 or Rb. Recent studies also explore its role in aging and chemotherapy resistance. Validated in multiple species and sample types, the antibody serves as a key reagent for both basic research and clinical studies aiming to unravel TEDC1's mechanistic contributions to disease and therapeutic targeting.

       
关键字: TEDC1抗体;TEDC1;TEDC1 Antibody;

公司简介

是一家科研、开发、生产和销售为一体的科技型企业,
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,蛋白组学,细胞生物学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
普通会员
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:重组蛋白、抗体、生物试剂
  • 公司地址:青浦区
询盘

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