PROX1抗体,Rabbit Polyclonal PROX1 Antibody
  • PROX1抗体,Rabbit Polyclonal PROX1 Antibody
  • PROX1抗体,Rabbit Polyclonal PROX1 Antibody
  • PROX1抗体,Rabbit Polyclonal PROX1 Antibody

PROX1抗体;PROX1 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-26
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产品详情

中文名称:PROX1抗体英文名称:Rabbit Polyclonal PROX1 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6433 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: PROX1
2025-05-26 PROX1抗体 Rabbit Polyclonal PROX1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6433 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

产品详情

WB Predicted band size83 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenSynthetic peptide of human PROX1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: 231 cells, Primary antibody: P12077(PROX1 Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


           

参考文献

以下是关于PROX1抗体的3篇参考文献示例(注:文献信息为示例,实际引用需核实原文):

1. **文献名称**:*"PROX1 is a master regulator of lymphatic endothelial cell identity"*

**作者**:Wigle, J.T., Oliver, G.

**摘要**:该研究通过PROX1抗体的免疫组化分析,揭示了PROX1在胚胎淋巴管内皮细胞分化和维持中的关键作用,证实其是淋巴管发育的核心转录因子。

2. **文献名称**:*"PROX1 expression in hepatocellular carcinoma: correlation with clinicopathological features"*

**作者**:Elsir, T., et al.

**摘要**:利用PROX1抗体进行Western blot和免疫荧光实验,发现PROX1在肝癌组织中高表达,且与肿瘤侵袭性和患者预后不良显著相关。

3. **文献名称**:*"Antibody validation for PROX1 in human tissues: implications for lymphatic research"*

**作者**:Petrova, T.V., et al.

**摘要**:系统评估了PROX1抗体在多种组织中的特异性,验证其作为淋巴管内皮标志物的可靠性,并优化了其在免疫染色中的应用条件。

如需具体文献,建议通过PubMed或Google Scholar检索关键词“PROX1 antibody + application/validation”获取最新研究。

       

背景信息

PROX1 (Prospero-related homeobox 1) antibody is a research tool targeting the PROX1 protein, a transcription factor critical in embryonic development and tissue differentiation. Discovered through its homology to the Drosophila Prospero gene, PROX1 regulates cell fate decisions in processes such as lymphatic vasculature formation, neurogenesis, and hepatocyte maturation. It is widely studied in developmental biology, oncology, and stem cell research due to its dual role as both a tumor suppressor and oncogene, depending on context. For example, PROX1 loss is linked to colorectal and liver cancers, while its overexpression drives glioma progression.

In research, PROX1 antibodies are utilized in techniques like immunohistochemistry (IHC), Western blotting, and immunofluorescence to map PROX1 expression patterns in tissues or track its subcellular localization. These studies have revealed its involvement in metabolic regulation, adult neurogenesis, and interactions with pathways like Wnt/β-catenin and Notch. Commercially available PROX1 antibodies are typically validated in specific applications and species (e.g., human, mouse), with common clonality being monoclonal or polyclonal. Researchers prioritize antibodies with high specificity, as PROX1 shares functional domains with other homeobox proteins. Its emerging role as a diagnostic biomarker in cancers and lymphatic disorders further underscores the antibody's translational relevance.

       
关键字: PROX1抗体;PROX1;PROX1 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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