PEG3抗体,Rabbit Polyclonal PEG3 Antibody
  • PEG3抗体,Rabbit Polyclonal PEG3 Antibody
  • PEG3抗体,Rabbit Polyclonal PEG3 Antibody
  • PEG3抗体,Rabbit Polyclonal PEG3 Antibody

PEG3抗体;PEG3 Antibody—艾普蒂

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-26
QQ交谈 微信洽谈

产品详情

中文名称:PEG3抗体英文名称:Rabbit Polyclonal PEG3 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 6734 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: PEG3
2025-05-26 PEG3抗体 Rabbit Polyclonal PEG3 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 6734 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/30-1/150 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesPW1; ZNF904; ZSCAN24; ZKSCAN22
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human PEG3
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       The image is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using P12586(PEG3 Antibody) at dilution 1/45. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P12586(PEG3 Antibody) at dilution 1/45. (Original magnification: ×200)    


           

参考文献

以下是3-4条关于PEG3抗体的参考文献示例(内容为虚构归纳,仅供参考):

1. **文献名称**: *PEG3 regulates placental development through epigenetic modifications*

**作者**: Kim, J. et al.

**摘要**: 本研究利用特异性PEG3抗体,通过免疫组化和Western blot分析发现,PEG3在胎盘滋养层细胞中高表达,并通过调控印记基因网络参与胚胎发育。

2. **文献名称**: *PEG3 antibody-based detection of tumor suppressor activity in glioblastoma*

**作者**: Smith, L. & Zhang, Y.

**摘要**: 开发了一种高灵敏度的PEG3单克隆抗体,证实其在胶质母细胞瘤组织中表达缺失,并验证其通过Wnt通路抑制肿瘤生长的机制。

3. **文献名称**: *Paternally expressed gene 3 (PEG3) modulates oxidative stress in neurons: Evidence from knockout mice and antibody labeling*

**作者**: Chen, H. et al.

**摘要**: 通过PEG3抗体免疫荧光染色,发现PEG3在小鼠脑神经元中定位在线粒体,敲除后导致抗氧化蛋白表达下降,提示其对神经保护的作用。

4. **文献名称**: *A novel PEG3 antibody reveals its role in DNA damage repair*

**作者**: Wang, R. et al.

**摘要**: 利用新开发的兔源多克隆抗体,证明PEG3与BRCA1蛋白相互作用,在乳腺癌细胞DNA损伤修复过程中发挥关键调控功能。

(注:以上文献为示例,实际引用需查询真实数据库如PubMed、Google Scholar。)

       

背景信息

The PEG3 (Paternally Expressed Gene 3) antibody is a research tool used to detect the PEG3 protein, a member of the zinc finger protein family encoded by an imprinted gene located on human chromosome 19q13.4. PEG3 is maternally silenced and paternally expressed, playing critical roles in embryonic development, cell proliferation, and apoptosis regulation. It is implicated in neural system development, placental function, and genomic imprinting mechanisms. Dysregulation of PEG3 has been associated with cancers (e.g., breast, ovarian), neurological disorders, and imprinting-related syndromes like Schaaf-Yang syndrome.

The PEG3 antibody enables researchers to study the protein's expression patterns, subcellular localization, and interactions via techniques like Western blotting, immunohistochemistry, and immunofluorescence. It is essential for investigating PEG3's tumor-suppressive functions, epigenetic regulation, and involvement in autophagy or oxidative stress pathways. Commercially available PEG3 antibodies are typically raised in rabbits or mice, validated for specificity using knockout controls or siRNA. Challenges include cross-reactivity with homologous proteins (e.g., PEG1. PEG5) and variability in tissue-specific isoforms. Recent studies leverage PEG3 antibodies to explore its role in metabolic reprogramming, stem cell differentiation, and as a potential biomarker for cancer prognosis. Proper validation and application-specific optimization remain crucial for reliable experimental outcomes.

       
关键字: PEG3抗体;PEG3;PEG3 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
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