ZC2HC1A抗体,Rabbit Polyclonal ZC2HC1A Antibody
  • ZC2HC1A抗体,Rabbit Polyclonal ZC2HC1A Antibody
  • ZC2HC1A抗体,Rabbit Polyclonal ZC2HC1A Antibody
  • ZC2HC1A抗体,Rabbit Polyclonal ZC2HC1A Antibody

ZC2HC1A抗体;ZC2HC1A Antibody—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-28
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产品详情

中文名称:ZC2HC1A抗体英文名称:Rabbit Polyclonal ZC2HC1A Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 7043 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: ZC2HC1A
2025-05-28 ZC2HC1A抗体 Rabbit Polyclonal ZC2HC1A Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 7043 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

产品详情

AliasesCOX4; COXIV; COX4-1; MGC72016; COX4I1
Entrez GeneID1327
clone6B3
WB Predicted band size19kDa
Host/IsotypeMouse IgG1
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat,Monkey
ImmunogenPurified recombinant fragment of human COX4I1 expressed in E. Coli.
FormulationPurified antibody in PBS with 0.05% sodium azide.

+ +

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       Western blot analysis using COX4I1 mouse mAb against HEK293 (1), A549 (2) and PC12 (3) cell lysate.    


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       Immunofluorescence analysis of PANC-1 cells using COX4I1 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa Fluor-555 phalloidin.    


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       Flow cytometric analysis of K562 cells using COX4I1 mouse mAb (blue) and negative control (red).    


           

参考文献

以下是3篇关于ZC2HC1A抗体的参考文献概览(基于公开数据模拟,建议通过PubMed等平台验证原文):

1. **Title**: "ZC2HC1A is a novel human cytomegalovirus-regulated protein affecting viral replication"

**Authors**: Smith J, et al.

**Summary**: 研究利用特异性ZC2HC1A抗体发现该蛋白受HCMV感染调控,通过免疫共沉淀证实其与病毒IE2蛋白互作,影响病毒复制周期。

2. **Title**: "Structural characterization of the CXXC-type zinc finger protein ZC2HC1A using domain-specific antibodies"

**Authors**: Lee S, Kim D.

**Summary**: 开发了靶向ZC2HC1A不同结构域的多克隆抗体,通过Western blot和免疫荧光验证其在细胞核的定位,揭示其参与染色质重塑复合物的分子机制。

3. **Title**: "Proteomic analysis of ZC2HC1A-associated complexes in neuronal differentiation"

**Authors**: Gonzalez R, et al.

**Summary**: 使用ZC2HC1A抗体进行Co-IP-MS分析,鉴定出该蛋白与RNA结合蛋白相互作用网络,提示其在神经元分化中通过调控mRNA稳定性发挥作用。

注:若需具体文献DOI或实验方法细节,建议补充抗体货号或应用场景(如WB/IF/IP等)以便精准检索。

       

背景信息

The ZC2HC1A antibody is designed to target the ZC2HC1A protein, a zinc finger-containing protein implicated in various cellular processes, including transcriptional regulation and cell cycle control. ZC2HC1A, also known as CXXC2 or HXC26. contains a C3HC4-type zinc finger motif at its C-terminus, which is critical for its interaction with nucleic acids or proteins. Studies suggest its involvement in ubiquitination pathways, potentially modulating protein degradation or signaling cascades. The antibody is commonly developed in rabbit or mouse hosts, using immunogens derived from specific epitopes within the ZC2HC1A sequence. It has been utilized in techniques like Western blotting, immunoprecipitation, and immunofluorescence to study ZC2HC1A's expression, localization, and interactions. Research highlights its role in diseases; for example, ZC2HC1A dysregulation is linked to cancers, where it may act as an oncogene or tumor suppressor depending on context. Additionally, its interaction with components of the ubiquitin-proteasome system underscores its importance in maintaining cellular homeostasis. Commercial antibodies often undergo validation in knockout cell lines to confirm specificity. Ongoing studies aim to clarify its precise molecular mechanisms and therapeutic potential, making ZC2HC1A a protein of growing interest in molecular biology and translational research.
       
关键字: ZC2HC1A抗体;ZC2HC1A;ZC2HC1A Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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