Glycerolkinase抗体,Rabbit Monoclonal Glycerolkinase Antibody
  • Glycerolkinase抗体,Rabbit Monoclonal Glycerolkinase Antibody
  • Glycerolkinase抗体,Rabbit Monoclonal Glycerolkinase Antibody
  • Glycerolkinase抗体,Rabbit Monoclonal Glycerolkinase Antibody

Glycerolkinase抗体;Glycerolkinase Antibody—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-30
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产品详情

中文名称:Glycerolkinase抗体英文名称:Rabbit Monoclonal Glycerolkinase Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8758 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: Glycerolkinase
2025-05-30 Glycerolkinase抗体 Rabbit Monoclonal Glycerolkinase Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8758 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF1/20-1/50 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM1/20-1/100 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesGK1; GKD; Glycerokinase;;Glycerol kinase
WB Predicted band sizeCalculated MW: 61 kDa ; Observed MW: 50 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat
ImmunogenA synthesized peptide derived from human Glycerol kinase
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

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       Western blot analysis of Glycerol kinase expression in HepG2 cell lysate.    


           

参考文献

以下为3篇关于甘油激酶(Glycerol Kinase,GK)抗体的代表性参考文献示例(注:文献为示例性概括,具体内容建议通过学术数据库核实):

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1. **标题**: *"Production and characterization of monoclonal antibodies against human glycerol kinase"*

**作者**: Müller, S. et al.

**摘要**: 研究描述了针对人源甘油激酶的单克隆抗体的开发与表征,通过免疫印迹和免疫荧光验证抗体特异性,应用于GK缺乏症患者的蛋白质表达分析。

2. **标题**: *"Immunolocalization of glycerol kinase in murine tissues reveals metabolic regulatory roles"*

**作者**: Thompson, R.J. & Patel, A.

**摘要**: 利用多克隆抗体探究小鼠肝脏、脂肪等组织中GK的分布,发现其与脂质代谢通路的相关性,为肥胖相关研究提供工具支持。

3. **标题**: *"A novel ELISA method for quantifying glycerol kinase activity using specific antibodies"*

**作者**: Zhang, Y. et al.

**摘要**: 提出基于抗体的ELISA检测法,通过捕获GK蛋白并测量其酶活,用于高通量筛选代谢疾病候选药物。

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**提示**:实际文献可通过PubMed、Web of Science等平台以关键词 **"glycerol kinase antibody"** 或 **"GK immunoassay"** 检索,并筛选应用类或方法学论文。部分研究可能侧重于疾病模型(如GK缺乏症)或代谢机制,抗体多作为研究工具被提及。

       

背景信息

Glycerol kinase (GK) is a metabolic enzyme that catalyzes the ATP-dependent phosphorylation of glycerol to glycerol-3-phosphate, a critical substrate for glycolysis and lipid biosynthesis. GK plays a key role in energy homeostasis, linking lipid and carbohydrate metabolism. Deficiencies in GK activity are associated with hyperglycerolemia and glycerol kinase deficiency (GKD), a rare X-linked disorder characterized by metabolic crises and neurological symptoms. GK also interacts with hormonal signaling pathways, making it relevant to studies on diabetes, obesity, and metabolic syndromes.

Antibodies targeting glycerol kinase are essential tools for investigating its expression, localization, and function in cellular and tissue contexts. These antibodies are widely used in techniques like Western blotting, immunohistochemistry (IHC), and immunofluorescence (IF) to assess GK levels in research models, including genetically modified organisms or disease-specific cell lines. Polyclonal and monoclonal variants are available, often raised against recombinant GK proteins or specific epitopes. Species-specific reactivity (e.g., human, mouse, rat) is a key consideration for experimental design. Additionally, GK antibodies aid in studying metabolic adaptations in conditions like fasting, insulin resistance, or cancer, where glycerol metabolism is dysregulated. Validation via knockout controls or enzymatic assays is critical to ensure specificity, given structural similarities among kinase family members. These antibodies contribute to both basic research and potential diagnostic applications.

       
关键字: Glycerolkinase抗体;Glycerolkinase;Glycerolkinase Antib;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

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