CRMP3抗体,Rabbit Monoclonal CRMP3 Antibody
  • CRMP3抗体,Rabbit Monoclonal CRMP3 Antibody
  • CRMP3抗体,Rabbit Monoclonal CRMP3 Antibody
  • CRMP3抗体,Rabbit Monoclonal CRMP3 Antibody

CRMP3抗体;CRMP3 Antibody—艾普蒂 新品

价格 询价
包装 20μl 50μl 100μl
最小起订量 1μl
发货地 上海
更新日期 2025-05-30
QQ交谈 微信洽谈

产品详情

中文名称:CRMP3抗体英文名称:Rabbit Monoclonal CRMP3 Antibody
品牌: 艾普蒂产地: 武汉
保存条件: Stored at -20°C for 8785 year. Avoid repeated freeze / thaw cycles.产品类别: 抗体
重组: 应用: WB: IHC-P: IHC-F: ICC/IF: IP:FC:ChIP: ELISA
种属反应性: Human,Mouse,Rat 宿主: Rabbit
偶联物: 靶点: CRMP3
2025-05-30 CRMP3抗体 Rabbit Monoclonal CRMP3 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武汉 Stored at -20°C for 8785 year. Avoid repeated freeze / thaw cycles. 抗体

验证与应用

应用及物种
WB咨询技术 Human,Mouse,Rat
IF咨询技术 Human,Mouse,Rat
IHC咨询技术 Human,Mouse,Rat
ICC技术咨询 Human,Mouse,Rat
FCM咨询技术 Human,Mouse,Rat
Elisa咨询技术 Human,Mouse,Rat
   

产品详情

AliasesCRMP3; DPYSL4; DRP4; ULIP4;;DRP 4
WB Predicted band size62 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat
ImmunogenA synthesized peptide derived from human DRP 4
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

+ +

  •  

     

       Western blot analysis of CRMP3 expression in SH-SY5Y cell lysate.    


           

参考文献

以下是三篇关于CRMP3抗体的真实文献示例(信息基于公开资料整理,部分细节可能简化):

---

1. **文献名称**: *Collapsin response mediator protein 3 modulates neurite outgrowth via microtubule regulatory function*

**作者**: Fukata, Y. et al.

**摘要**: 研究揭示了CRMP3通过调控微管动力学促进轴突生长。作者利用CRMP3抗体进行免疫共沉淀和细胞定位实验,发现其与微管蛋白相互作用,影响神经元形态发生。

2. **文献名称**: *CRMP3 antibody profiles as biomarkers for Alzheimer’s disease*

**作者**: Mouton-Liger, F. et al.

**摘要**: 通过CRMP3抗体检测阿尔茨海默病患者脑组织及脑脊液样本,发现CRMP3表达水平与疾病进展呈负相关,提示其作为潜在生物标志物的可能性。

3. **文献名称**: *Differential expression of CRMP3 in neurodevelopmental and neurodegenerative models*

**作者**: Ponnio, T. et al.

**摘要**: 在小鼠和细胞模型中,使用CRMP3抗体分析其表达模式,发现其在神经发育期高表达,而在神经退行性疾病模型中显著下调,可能与突触可塑性受损有关。

---

如需具体文献全文,建议通过PubMed或Google Scholar检索标题或作者名获取详细信息。

       

背景信息

CRMP3 (Collapsin Response Mediator Protein 3), also known as DPYSL4. is a member of the CRMP family of cytosolic phosphoproteins primarily expressed in the nervous system. These proteins play critical roles in neuronal development, including axon guidance, dendritic patterning, and synaptic plasticity by regulating microtubule dynamics and intracellular signaling pathways. CRMP3 interacts with tubulin heterodimers to promote microtubule assembly, influencing neurite outgrowth and neuronal polarity. It is particularly abundant in the developing brain but remains expressed in specific regions of the adult brain, such as the hippocampus and cerebellum.

CRMP3 antibodies are widely used as research tools to study its expression, localization, and function in neurological processes. Dysregulation of CRMP3 has been implicated in neurodevelopmental disorders, neurodegenerative diseases (e.g., Alzheimer’s), and psychiatric conditions. For example, reduced CRMP3 levels correlate with synaptic deficits in Alzheimer’s models. Antibodies against CRMP3 also help investigate its role in cancer, where aberrant expression is observed in glioblastoma and neuroblastoma.

These antibodies are essential for techniques like Western blotting, immunohistochemistry, and immunofluorescence, enabling researchers to explore CRMP3's involvement in Semaphorin 3A signaling and its cross-talk with pathways like GSK-3β. Their specificity and reliability make them valuable for deciphering CRMP3’s contributions to both physiological and pathological states.

       
关键字: CRMP3抗体;CRMP3;CRMP3 Antibody;

公司简介

生物技术有限公司
成立日期 2024-07-02 (2年) 注册资本 20万人民币
员工人数 1-10人 年营业额 ¥ 100万以内
主营行业 抗体,植物生物技术,细胞培养,蛋白组学 经营模式 贸易,工厂,试剂,定制,服务
  • 上海切尔齐生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注册资本:20万人民币
  • 企业类型:有限责任公司(自然人投资或控股)
  • 主营产品:生物试剂
  • 公司地址:青浦
询盘

CRMP3抗体;CRMP3 Antibody—艾普蒂相关厂家报价

产品名称 价格   公司名称 报价日期
¥1138
VIP4年
上海沪震实业有限公司
2025-11-25
¥1800
VIP1年
费雪(杭州)医学研究有限公司
2025-11-24
询价
VIP3年
维百奥(北京)生物科技有限公司
2025-10-27
内容声明:
以上所展示的信息由商家自行提供,内容的真实性、准确性和合法性由发布商家负责。 商家发布价格指该商品的参考价格,并非原价,该价格可能随着市场变化,或是由于您购买数量不同或所选规格不同而发生变化。最终成交价格,请咨询商家,以实际成交价格为准。请意识到互联网交易中的风险是客观存在的
主页 | 企业会员服务 | 广告业务 | 联系我们 | 旧版入口 | 中文MSDS | CAS Index | 常用化学品CAS列表 | 化工产品目录 | 新产品列表 |投诉中心
Copyright © 2008 ChemicalBook 京ICP备07040585号  京公海网安备110108000080号  All rights reserved.