Human CCL27 Protein, His Tag
分子别名(Synonym)
ALP, CTACK, CTAK, ESKINE, ILC, PESKY, SCYA27
表达区间及表达系统(Source)
Human CCL27 Protein, His Tag (CC7-H5143) is expressed from E. coli cells. It contains AA Phe 25 - Gly 112 (Accession # Q9Y4X3).
Predicted N-terminus: Met
蛋白结构(Molecular Characterization)

This protein carries a polyhistidine tag at the N-terminus.
The protein has a calculated MW of 12.2 kDa. The protein migrates as 11 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
内毒素(Endotoxin)
Less than 1.0 EU per μg by the LAL method / rFC method.
纯度(Purity)
>90% as determined by SDS-PAGE.
制剂(Formulation)
Lyophilized from 0.22 μm filtered solution in PBS, 0.2 M Arginine, pH7.3 with trehalose as protectant.
Contact us for customized product form or formulation.
重构方法(Reconstitution)
Please see Certificate of Analysis for specific instructions.
For best performance, we strongly recommend you to follow the reconstitution protocol provided in the CoA.
存储(Storage)
For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Please avoid repeated freeze-thaw cycles.
This product is stable after storage at:
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution.

背景介绍
该基因位于9号染色体短臂(p-arm),是与多个CC趋化因子基因聚集于此的基因簇成员之一。细胞因子作为参与免疫调节与炎症反应的分泌蛋白家族,其CC亚型以两个相邻半胱氨酸为结构特征。本基因编码的蛋白质对皮肤归巢记忆T淋巴细胞具有趋化活性,该细胞因子还介导淋巴细胞向皮肤组织的定向迁移。它能特异性结合趋化因子受体CCR10(chemokine receptor 10)。基于小鼠同源蛋白的研究表明,此类蛋白-受体相互作用在T细胞介导的皮肤炎症中发挥枢纽作用。
关键字: CCL27;CCL27蛋白;CCL27重组蛋白;ACRO;百普赛斯;
百普赛斯集团ACROBiosystems Group(股票代码:301080)是成立于2010年的跨国生物科技公司,是为全球生物医药、健康产业领域提供关键生物试剂产品及解决方案的行业平台型基石企业。2021年在创业板上市。百普赛斯集团业务遍布全球,横跨亚洲、北美洲、欧洲,在中国、美国、瑞士等12个城市设有办公室、研发中心及生产基地。目前累计服务客户超6000家,与全球Top 20医药企业均建立了长期、稳定的合作伙伴关系。集团旗下拥有品牌ACROBiosystems百普赛斯、bioSeedin柏思荟、Condense Capital垦拓资本和ACRODiagnostics百斯医学等。