产品概述
ATP Citrate Lyase (3D9) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,ICC/IF,FC
Human,Mouse,Monkey
产品性能
Unconjugated
Unmodified
IgG2a
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
ACLY
ACLY; ATP-citrate synthase; ATP-citrate; pro-S-)-lyase; ACL; Citrate cleavage enzyme
47
P53396
产品应用
WB: 1:500-1:1000 IF: 1:50-1:200 FC: 1:50-1:100
Calculated MW: 121 kDa; Observed MW: 121 kDa
研究背景
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis.
研究领域
Signal Transduction
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