产品概述
ZAP70 (4B2) Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
WB,IP
Human
产品性能
Unconjugated
Unmodified
IgG2b
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Affinity Purification
免疫原
ZAP70
ZAP70; SRK; Tyrosine-protein kinase ZAP-70; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase
7535
P43403
产品应用
WB: 1:500-1:1000 IP: 1:20
Calculated MW: 70 kDa; Observed MW: 70 kDa
研究背景
The Syk family protein tyrosine kinase Zap-70 is expressed in T and NK cells and plays a critical role in mediating T cell activation in response to T cell receptor (TCR) engagement. Following TCR engagement, Zap-70 is rapidly phosphorylated on several tyrosine residues through autophosphorylation and transphosphorylation by the Src family tyrosine kinase Lck.
研究领域
Immunology
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