产品概述
NBR1(7C3)Mouse Monoclonal Antibody
Mouse Monoclonal Antibody
Mouse
IF-P,IF-F,ICC/IF,IHC-P
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
NBR1
Next to BRCA1 gene 1 protein (Cell migration-inducing gene 19 protein) (Membrane component chromosome 17 surface marker 2) (Neighbor of BRCA1 gene 1 protein) (Protein 1A1-3B)
4077
Q14596
产品应用
IF-P/IF-F/ICC/IF 1:50-200, IHC-P 1:50-300
120kDa
研究背景
The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014],caution:Was originally (PubMed:8069304) thought to be the ovarian carcinoma antigen CA125.,domain:The OPR domain mediates interaction with SQSTM1.,similarity:Contains 1 OPR domain.,similarity:Contains 1 UBA domain.,similarity:Contains 1 ZZ-type zinc finger.,subunit:Homooligomer and heterooligomer. Interacts with SQSTM1, titin/TTN and RNF29.,
研究领域
武汉恩玑生命科技有限公司
联系商家时请提及chemicalbook,有助于交易顺利完成!
在线客服