产品概述
MLH1 Rabbit Monoclonal Antibody
Rabbit Monoclonal antibody
Rabbit
WB
Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal Antibody
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Affinity Purification
免疫原
MLH1
MLH1; COCA2; DNA mismatch repair protein Mlh1; MutL protein homolog 1
4292
P40692
产品应用
WB: 1:500-1:1000
Calculated MW: 85 kDa; Observed MW: 85 kDa
研究背景
This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Alternatively spliced transcript variants encoding different isoforms have been described, but their full-length natures have not been determined.
研究领域
Epigenetics and Nuclear Signaling
武汉恩玑生命科技有限公司
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