产品概述
KAT8 / MYST1 / MOF (9E16) Rabbit Monoclonal Antibody
Rabbit Monoclonal Antibody
Rabbit
WB,IHC-P,ICC/IF,FC,IP,IF-P
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% New type preservative N and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle.
Affinity purification
免疫原
KAT8
hMOF; MOF; MOZ; MYST1; SAS2; SAS3; YBF2; YBF2/SAS3; ZC2HC8;
84148
Q9H7Z6
产品应用
WB 1:1000, IHC-P/IF-P 1:200-1:500, ICC/IF 1:500-1:2000, FCM 1:100-1:200, IP 1:100-1:200
52kDa
研究背景
Histone acetyltransferase which may be involved in transcriptional activation. May influence the function of ATM. Histone acetyltransferase which may be involved in transcriptional activation (PubMed:12397079, PubMed:22020126). May influence the function of ATM (PubMed:15923642). As part of the MSL complex it is involved in acetylation of nucleosomal histone H4 producing specifically H4K16ac (PubMed:16227571, PubMed:16543150, PubMed:21217699, PubMed:22547026, PubMed:22020126). As part of the NSL complex it may be involved in acetylation of nucleosomal histone H4 on several lysine residues (PubMed:20018852, PubMed:22547026). That activity is less specific than the one of the MSL complex (PubMed:20018852, PubMed:22547026). Can also acetylate TP53/p53 at 'Lys-120'.
研究领域
武汉恩玑生命科技有限公司
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