产品概述
STARD4 Rabbit Monoclonal antibody
Rabbit Monoclonal antibody
Rabbit
WB,IF,ICC
Human
产品性能
Unconjugated
Unmodified
IgG,Kappa
Monoclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Protein A
免疫原
STARD4
STARD4;StAR-related lipid transfer protein 4 ;START domain-containing protein 4;StARD4;
134429
Q96DR4
产品应用
WB 1:1000-5000;ICC/IF 1:100-300
Calculated MW:;Observed MW:23kD
研究背景
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD4 (Soccio et al., 2002 [PubMed 12011452]).[supplied by OMIM, Mar 2008]
研究领域
武汉恩玑生命科技有限公司
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