产品概述
GATA-3 (phospho Ser308) Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IF-P,IF-F,ICC/IF,ELISA
Human,Mouse
产品性能
Unconjugated
Phospho Antibody
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
GATA3
GATA3; Trans-acting T-cell-specific transcription factor GATA-3; GATA-binding factor 3
2625
P23771
产品应用
WB 1:500-2000, IF-P/IF-F/ICC/IF 1:200-1:1000, ELISA 1:10000.Not yet tested in other applications.
研究背景
This gene encodes a protein which belongs to the GATA family of transcription factors. The protein contains two GATA-type zinc fingers and is an important regulator of T-cell development and plays an important role in endothelial cell biology. Defects in this gene are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia. [provided by RefSeq, Nov 2009],disease:Defects in GATA3 are the cause of hypoparathyroidism with sensorineural deafness and renal dysplasia (HDR) [MIM:146255]; also known as Barakat syndrome.,function:Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5'-AGATAG-3'.,similarity:Contains 2 GATA-type zinc fingers.,tissue specificity:T-cells and endothelial cells.,
研究领域
武汉恩玑生命科技有限公司
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