产品概述
TGFβ RIII Rabbit Polyclonal Antibody
Rabbit Polyclonal Antibody
Rabbit
WB,IF-P,IF-F,ICC/IF,ELISA
Human,Mouse,Rat
产品性能
Unconjugated
Unmodified
IgG
Polyclonal
Liquid
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Affinity purification
免疫原
TGFBR3
TGFBR3; Transforming growth factor beta receptor type 3; TGF-beta receptor type 3; TGFR-3; Betaglycan; Transforming growth factor beta receptor III; TGF-beta receptor type III
7049
Q03167
产品应用
WB 1:500-2000, IHC 1:100-1:300, ELISA 1:5000, IF-P/IF-F/ICC/IF 1:50-200
研究背景
This locus encodes the transforming growth factor (TGF)-beta type III receptor. The encoded receptor is a membrane proteoglycan that often functions as a co-receptor with other TGF-beta receptor superfamily members. Ectodomain shedding produces soluble TGFBR3, which may inhibit TGFB signaling. Decreased expression of this receptor has been observed in various cancers. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.[provided by RefSeq, Sep 2010],function:Binds to TGF-beta. Could be involved in capturing and retaining TGF-beta for presentation to the signaling receptors.,PTM:Extensively modified by glycosaminoglycan groups (GAG).,similarity:Contains 1 ZP domain.,subcellular location:Exists both as a membrane-bound form and as soluble form in serum and in the extracellular matrix.,subunit:Interacts with TCTEX1D4.,
研究领域
武汉恩玑生命科技有限公司
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