产品概述
| 产品名称(Product Name) | Integrin αL Rabbit Polyclonal Antibody | 
| 描述(Description) | Rabbit Polyclonal Antibody | 
| 宿主(Host) |  Rabbit | 
| 应用(Application) | WB,ELISA | 
| 种属反应性(Reactivity) | Human,Rat,Mouse  | 
 
产品性能
| 偶联物(Conjugation) | Unconjugated | 
| 修饰(Modification) | Unmodified | 
| 同种型(Isotype) | IgG | 
| 克隆(Clonality) | Polyclonal | 
| 形式(Form) | Liquid | 
| 存放说明(Storage) | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. | 
| 储存溶液(Buffer) | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N. | 
| 纯化方式(Purification) | Affinity purification | 
 
免疫原
| 基因名(Gene Name) | ITGAL | 
| 别名(Alternative Names) | ITGAL; CD11A; Integrin alpha-L; CD11 antigen-like family member A; Leukocyte adhesion glycoprotein LFA-1 alpha chain; LFA-1A; Leukocyte function-associated molecule 1 alpha chain; CD11a | 
| 基因ID(Gene ID) | 3683 | 
| 蛋白ID(SwissProt ID) | P20701 | 
 
产品应用
| 稀释比(Dilution Ratio) | WB 1:500-1:2000, ELISA 1:10000.Not yet tested in other applications. | 
| 蛋白分子量(Molecular Weight) | 130kDa | 
 
研究背景
integrin subunit alpha L(ITGAL) Homo sapiens    ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],domain:The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.,function:Integrin alpha-L/beta-2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. It is involved in a variety of immune phenomena including leukocyte-endothelial cell interaction, cytotoxic T-cell mediated killing, and antibody dependent killing by granulocytes and monocytes.,similarity:Belongs to the integrin alpha chain family.,similarity:Contains 1 VWFA domain.,similarity:Contains 7 FG-GAP repeats.,subunit:Heterodimer of an alpha and a beta subunit. Alpha-L associates with beta-2.,tissue specificity:Leukocytes.,
 
研究领域
Cell adhesion molecules (CAMs);Natural killer cell mediated cytotoxicity;Leukocyte transendothelial migration;Regulates Actin and Cytoskeleton;Viral myocarditis;
关键字: ITGAL;Integrin;αL;Rabbit;Polyclonal;Antibody;一抗
                                武汉恩玑生命科技有限公司(EnkiLife)是一家深耕生命科学,专注细胞生物学和免疫学科研试剂的研发、生产与销售的生物技术企业,在全球100多个国家和地区开展业务,致力于为科研工作者提供高质量的产品和卓越的客户服务,推动生命科学的发展。
EnkiLife的产品线涵盖细胞系、原代细胞、细胞培养基、血清、细胞检测试剂盒、重组靶点蛋白、细胞因子、重组抗体、ELISA试剂盒、生化试剂盒等,并提供技术服务与定制开发,覆盖了生命科学研究的各大关键领域,包括细胞生物学、癌症、免疫学、神经科学、心血管疾病、干细胞、表观遗传学、内分泌、蛋白质组学、代谢组学等,全方位满足您的实验需求,让您享受科研的乐趣!
公司现已建立四大技术平台:
EnCyto?细胞培养及检测平台:拥有细胞系库(500+)、原代细胞库(500+)、基础培养基和完全培养基(1200+)
EnkiPro?重组蛋白平台:现货产品2000+,可提供定制化表达服务
EnAb?重组抗体平台:重组兔单抗(3000+),可提供定制化和标记服务
EnKits?试剂盒开发平台:可提供优质的ELISA试剂盒、配套试剂、抗体对、生化试剂盒等相关产品
EnkiLife在生产管理方面引入ISO9001质量管理体系和信息化、自动化的管理工具,拥有高效稳定的交付能力,与全球知名品牌建立了紧密的合作。
EnkiLife始终坚持以技术创新为驱动,以匠心铸就品质,以品质服务客户。
我们期待与更多的全球科研工作者和企业携手合作,共同推动生命科学领域的进步与发展。