货号:GS40818
Zigakibart is an investigational humanized monoclonal antibody of the IgG4 isotype that specifically targets and neutralizes A Proliferation-Inducing Ligand (APRIL). It is being developed for the treatment of autoimmune diseases driven by pathogenic B cells and autoantibodies, such as systemic lupus erythematosus (SLE) and IgA nephropathy (IgAN), aiming to disrupt B cell survival and class-switching.
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