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品牌:MedChemExpress (MCE)
货号:HY-P84932
运输条件:用蓝冰运输。
产品活性:Mucin 1 Antibody 是无偶联基团的、靶向 Mucin 1 的 IgG 抗体。Mucin 1 Antibody可用于人背景下的 IHC, IF,ELISA实验。
研究背景:The related gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. The protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. The protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of The protein have been associated with carcinomas. The related gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
宿主:Rabbit
反应物种:Human
推荐稀释比例:IHC: 1:20-1:200; IF: 1:50-1:200; ELISA: 1: 2000-1:5000
基因 ID:4582 [NCBI]
同用名:MUC1; PUM; Mucin-1; MUC-1; Breast carcinoma-associated antigen DF3; Carcinoma-associated mucin; Episialin; H23AG; Krebs von den Lungen-6; KL-6; PEMT; Peanut-reactive urinary mucin; PUM; Polymorphic epithelial mucin; PEM; Tumor-associated ep
克隆性:Polyclonal
偶联:Non-conjugated
修饰:Unmodified
蛋白数据库:P15941-8
同型:IgG
详情参考:www.medchemexpress.cn/antibody/mucin-1-antibody-ya4629.html
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