Product Name:BM213
CAS No.:2891606-02-1
Synonyms:选择性C5aR激动剂
Catalog No.:220P319
Brand:Typeptide Biotech(肽研生物)
Description:BM213是一种选择性C5aR激动剂多肽,序列中含有8个氨基酸,其半数有效浓度 (EC50) 为 59 nM。BM213 特异性激活 C5a-C5aR1 轴,进而促进中性粒细胞胞外陷阱 (NET) 形成并加剧炎症反应。BM213 显著诱导大鼠心室扩张,促进心肌 ROS 产生,并诱导心肌细胞 apoptosis。BM213 可用于研究心肌缺血/再灌注 (I/R) 损伤。
BM213 is a selective C5aR agonist peptide containing 8 amino acids in its sequence, with an EC50 of 59 nM. BM213 specifically activates the C5a-C5aR1 axis, promoting the formation of neutrophil extracellular traps (NETs) and exacerbating inflammatory responses. BM213 significantly induces ventricular dilation in rats, promotes myocardial ROS production, and induces cardiomyocyte apoptosis. BM213 can be used to study myocardial ischemia/reperfusion (I/R) injury.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility:H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Ac-FKPLAAAR |
Sequence(3-letter code) | Ac-Phe-Lys-Pro-Leu-Ala-Ala-Ala-Arg-OH |
Peptide Structure | 
|
Molecular Formula | C43H70N12O10 |
Molecular Weight | 915.09 |
订购联系方式:
南京肽研生物生物科技有限公司
手机号:19961912513(微信同号)
QQ: 2178255659
邮箱:sales@typeptide.com
联系人:顾经理
申明:本产品仅供科研使用,不得用于人体。
关键字: BM213;选择性C5aR激动剂;2891606-02-1;多肽;多肽合成;
肽研生物坐落于国家级新区南京江北新区新材料产业园,是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神,持续投入研发,不断创新,致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。