(Infliximab)Biosimilar Reference Antibody-GS40338

货号：GS40338

Infliximab (brand name Remicade® among others) is a chimeric monoclonal IgG1κ antibody approved for the treatment of several chronic immune-mediated inflammatory diseases. It functions as a tumor necrosis factor-alpha (TNF-α) inhibitor. By binding with high affinity to both soluble and transmembrane forms of TNF-α, infliximab neutralizes its biological activity, preventing TNF-α from interacting with its receptors, TNFR1 and TNFR2. This blockade inhibits the downstream pro-inflammatory signaling cascade that drives chronic inflammation, tissue damage, and symptoms in a range of autoimmune conditions.