Product Name：P110
CAS No.：2770267-63-3
Synonyms：功能性细胞穿膜肽P110
Catalog No.：217P626
Brand：Typeptide Biotech（肽研生物）
Description：P110是一种带有穿透细胞膜的功能性多肽，序列中含有20个氨基酸，稳定性较好。Drp1 peptide inhibitor P110 (Compound P110) 是选择性的 Drp1 肽抑制剂，具有神经保护作用。Drp1 peptide inhibitor P110 可抑制 Drp1 的激活，阻止 MPTP 诱导的 Drp1 线粒体转移，并减轻 MPTP 导致的多巴胺能神经元丢失、多巴胺能神经末梢损伤和行为缺陷，可以用于阿尔兹海默症的研究。Drp1 peptide inhibitor P110 还可减轻亨廷顿病、脑缺血损伤和心肌梗死动物模型中的线粒体损伤和器官损伤。
P110 is a functional peptide with the ability to penetrate cell membranes, containing 20 amino acids in its sequence and exhibiting good stability. P110 is a selective Drp1 peptide inhibitor with neuroprotective effects. Drp1 peptide inhibitor P110 can inhibit the activation of Drp1, prevent MPTP induced mitochondrial transfer of Drp1, and alleviate MPTP induced loss of dopaminergic neurons, damage to dopaminergic nerve endings, and behavioral defects. It can be used for research on Alzheimer's disease. Drp1 peptide inhibitor P110 can also alleviate mitochondrial damage and organ damage in animal models of Huntington's disease, cerebral ischemic injury, and myocardial infarction.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | YGRKKRRQRRRGGDLLPRGS-NH2 |
Sequence(3-letter code) | H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Gly-Gly-Asp-Leu-Leu-Pro-Arg-Gly-Ser-NH2 |
Peptide Structure | 
|
Molecular Formula | C100H179N45O25 |
Molecular Weight | 2411.8 |
订购联系方式：
南京肽研生物生物科技有限公司
手机号：19961912513(微信同号)
QQ: 2178255659
邮箱：sales@typeptide.com
联系人：顾经理
申明：本产品仅供科研使用，不得用于人体。
关键字： P110;功能性细胞穿膜肽P110;2770267-63-3;多肽合成;多肽;
肽研生物坐落于国家级新区南京江北新区新材料产业园，是一家专业从事多肽产 品的研发、生产和销售以及多肽技术转让的高新技术企业。公司秉持“诚信、严 谨、务实”的匠人精神，持续投入研发，不断创新，致力于为科研工作者提供丰 富全面的多肽修饰类型和优质的产品。